UVB


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ultraviolet

 [ul″trah-vi´o-let]
denoting electromagnetic radiation of wavelength shorter than that of the violet end of the spectrum, having wavelengths of 4–400 nanometers.
ultraviolet A (UVA) ultraviolet radiation with wavelengths between 320 and 400 nm, comprising over 99 per cent of such radiation that reaches the surface of the earth. Ultraviolet A enhances the harmful effects of ultraviolet B radiation and is also responsible for some photosensitivity reactions; it is used therapeutically in the treatment of a variety of skin disorders.
ultraviolet B (UVB) ultraviolet radiation with wavelengths between 290 and 320 nm, comprising less than 1 per cent of the ultraviolet radiation that reaches the earth's surface. Ultraviolet B causes sunburn and a number of damaging photochemical changes within cells, including damage to DNA, leading to premature aging of the skin, premalignant and malignant changes, and a variety of photosensitivity reactions; it is also used therapeutically for treatment of skin disorders.
ultraviolet C (UVC) ultraviolet radiation with wavelengths between 200 and 290 nm; all of this type of radiation is filtered out by the ozone layer so that none reaches the earth's surface. Ultraviolet C is germicidal and is also used in ultraviolet phototherapy.
ultraviolet rays electromagnetic radiation beyond the violet end of the visible spectrum; they are not visible to humans. They are produced by the sun but are absorbed to a large extent by particles of dust and smoke in the earth's atmosphere. They are also produced by the so-called sun lamps. They can produce sunburn and affect skin pigmentation, causing tanning. When they strike the skin surface they transform provitamin D, secreted by the glands of the skin, into vitamin D, which is then absorbed into the body. Because ultraviolet rays are capable of killing bacteria and other microorganisms, they are sometimes used to sterilize objects in specially designed cabinets, or to sterilize the air in operating rooms and other areas where destruction of bacteria is necessary.
ultraviolet therapy the employment of ultraviolet radiation in the treatment of diseases, particularly those affecting the skin. See also PUVA therapy and photochemotherapy. Among the diseases that respond to this form of therapy are acne vulgaris, psoriasis, and external ulcers.

Dosage. The dosage unit of ultraviolet radiation is expressed as minimal erythema dose (MED). Because of varying degrees of skin thickness and pigmentation, human skin varies widely in its sensitivity to ultraviolet radiation. The MED refers to the amount of radiation that will produce, within a few hours, minimal erythema (redness caused by engorgement of capillaries) in the average Caucasian skin. Dosage for individual patients is prescribed according to probable sensitivity as determined by that individual's skin type as compared to average sensitivity.
Degrees of Erythema. Minimal erythema is a first degree erythema and usually is produced after about 15 seconds of exposure to a high-pressure mercury arc in a quartz burner placed at a distance of 75 cm (30 in) from the skin. A second degree erythema results from a dose of about 2.5 MED; its effects become apparent about 4 to 6 hours after application and are followed by slight peeling of the skin. A third degree erythema is produced by about 5 MED; it may become apparent within 2 hours after application and is accompanied by edema followed by marked desquamation. A fourth degree erythema is produced by about 10 MED and is characterized by blistering.
Precautions. Ultraviolet therapy is safe only in the hands of a skilled and knowledgeable therapist. Areas of “thin skin” that may be burned more readily than that receiving treatment must be protected by wet towels or dressings. The eye is highly sensitive to ultraviolet radiation; therefore some form of protection, such as goggles, compresses, or cotton balls, should be provided for both the patient and the therapist to avoid damage to the conjunctiva and cornea.



Certain drugs, such as the sulfonamides, greatly increase sensitivity to ultraviolet radiation. All patients scheduled for this form of therapy should be questioned in regard to the medication they are taking so the dosage can be adjusted accordingly or the treatment deferred.

UVB

Abbreviation for ultraviolet B.

UVB

ultraviolet B; see ultraviolet.

UVB

(yo͞o′vē′bē′)
n.
Ultraviolet radiation that is found in sunlight, has a wavelength between 290 and 320 nanometers, and can cause damage to the skin including sunburn, tanning, premature aging, and cancer.

UVB

Abbreviation for ultraviolet B.
References in periodicals archive ?
Ct = (Cttarget − Ct[sz]-actin) sample − (Cttarget − Ct[sz]-actin) control, taking the mean of Ct in the HaCat cells without UVB exposure as the control.
Skin wrinkle formation was measured in hairless mice chronically exposed to UVB radiation for 8 weeks.
Narrow band UVB therapy in early stage mycosis fungoides.
As expected, UVB exposure increased protein levels of phospho-P53 (Ser15) and phosphohistone H2AX (Ser139), whereas MHY498 treatment appears to reverse them (Supplementary Figure 2).
Although we do not know the exact number of lizards recaptured during the UVB study, lizards at most of the 71 sighting locations were likely to be different individuals.
It "competes" for UVB with the substance in the skin that kickstarts the body's vitamin D production.
Professor Helen Macdonald, professor of nutrition and musculoskeletal health at the university, said: "We want to see whether giving volunteers vitamin D, or artificial UVB light, can counter the problem of lack of sunlight and improve our health.
Though it prevents UVB from penetrating your skin, studies of sunscreen's effects in practice have shown that its adverse influence on vitamin D are minimal.
These secretions, distributed on the feathers through preening, are photoconverted under UVB exposure to the active form of vitamin [D.
Patients were exposed to UVA or UVB, two hours after intake of 8-MOP(10 mg) tablet in a dose of 0.
Among nurses in the first NHS cohort, higher cumulative exposure to UVB was associated with a reduced risk of developing the disease.