DZIP3

(redirected from UURF2 ubiquitin ligase)

DZIP3

A gene on chromosome 3q13.13 that encodes an RNA-binding zinc finger protein which mediates ubiquitination and subsequent proteasomal degradation of target proteins. DZIP3 is primarily expressed in mature germ cells and secondary spermatocytes in the testes, and is thought to participate in spermatogenesis by interacting with DAZ proteins.