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Tzanck test
(redirected from Tzanck smear)

   Also found in: Wikipedia 0.01 sec.
Tzanck test
[tsangk]
Etymology: Arnault Tzanck, Russian dermatologist in France, 1886-1954
a microscopic examination of cellular material from skin lesions to help diagnose certain vesicular diseases. The tissue is scraped from the base of a vesicle, placed on a slide, and stained with Wright's or Giemsa's stain. Multinucleated giant cells are diagnostic of herpesvirus or varicella. Typical pemphigus and other cells also can be identified.


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Our laboratories were able to provide evidence of the virus through Pap or Tzanck smear examinations, but these smears can vary greatly in sensitivity and specificity and thus run a poor second to tissue culture methods, which are the gold standard for herpes virus identification.
 
 
 
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