Spitzer M, Chernys A, Seltzer V The use of large loop excision of the transformation zone
in an innercity population.
Sensitivity of the cervical transformation zone
to estrogen-induced squamous carcinogenesis.
Removal of the transformation zone
, with ablative or excisional treatment, is the recommended initial treatment
This phase also enabled the nurse to recognise the abnormal transformation zone
, perform biopsies and endocervical curettage.
A loop is a very thin stainless steel wire of 2-3 cm used for excision of transformation zone
with blended current, (cutting & coagulation) with low voltage output is used, tissue up to the depth of 10 mm or more can be removed.
14) Specimen adequacy was additionally reported, including the subcategories unsatisfactory and SBLB, considering (1) obscuring blood, (2) obscuring inflammation, (3) scant cellularity, (4) poor fixation, (5) mechanical damage, (6) cytolysis, (7) thick area, (8) too few squamous cells with predominantly endocervical cells, and (9) no endocervical or transformation zone
component (SBLB ec-).
The loop size is chosen according to the size of the lesion and the transformation zone
Two centimeters inside the anal canal is a transformation zone
where the rectal columnar epithelium meets the anal squamous epithelium.
Reasons for referral included incomplete visualization of the transformation zone
, significant discrepancy between cytology and histology, and high-grade lesions requiring laser or conization.
The sampling procedure is designed to collect an adequate number of representative well-preserved epithelial cells including cells from the transformation zone
Human papillomavirus DNA detection in ThinPrep Pap test vials is independent of cytologic sampling of the transformation zone