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transcription factor

   Also found in: Acronyms, Wikipedia 0.01 sec.
transcription factor,
a specific protein required for the initiation of transcription by an RNA polymerase. Each polymerase has its own set of transcription factors.


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During the study, researchers treated colon and breast cancer cell lines with alcohol and then looked for the biochemical hallmarks of the epithelial-to-mesenchymal transition, including evidence of a transcription factor called Snail and of the receptor for epidermal growth factor.
50 Hardcover QH603 The aims of this volume are to describe a range of molecular, structural, and cell biological protocols currently used to investigate the structure-function of nuclear receptors (a superfamily of ligand- activated transcription factors that act principally to directly control patterns of gene expression) and to discuss experimental approaches that may lead to new therapeutic strategies for treating nuclear receptor-associated diseases.
We assessed maximal leptin-mediated binding of the transcription factor signal transducer and activator of transcription 3 (STAT3), and the response to high-fat feeding in lean leptin-resistant rats.
 
 
 
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