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transaminase
(redirected from Transaminases)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
transaminase /trans·am·i·nase/ (-am´ĭ-nās) aminotransferase.
trans·am·i·nase (trns-m-ns, -nz, trnz-)

transaminase.
transaminase [trans-am´ĭ-nās]
any of a group of enzymes that catalyze the reversible transfer of an amino group from a donor, usually an amino acid, to an acceptor, usually a 2-keto acid. Most use pyridoxal phosphate as a coenzyme.

transaminase (transam´inās),
n one of several enzymes involved in the reversible transfer of an amino (NH2) group from an α-amino acid to an α-ketoacid, especially α-ketoglutaric acid. Characteristic high values are seen in myocardial infarction and viral hepatitis.

transaminase
an enzyme that catalyzes the transfer of an amino group from one molecule to another.

glutamic-oxaloacetic transaminase (GOT)
glutamic-pyruvic transaminase (GPT)


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However, transaminases are now elevated and histologically there is increased necroinflammatory activity.
The importance of this topic was also highlighted by the findings of a recent study presented at this year's Conference on Retroviruses and Opportunistic Infections in Montreal showing a high prevalence of hepatic fibrosis and steatosis in HIV/AIDS patients without chronic viral hepatitis but with chronically elevated transaminases on antiretroviral therapy [5].
The most frequent side effects related to the use of statins, myopathy, rhabdomyolysis, and increased levels of transaminases, are unusual.
 
 
 
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