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torsades de pointes

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torsades de pointes
[tôrsäd′ de pô·aNt′, tôr′sād də point′]
Etymology: Fr, torsader, to twist together, pointes, tips
a type of ventricular tachycardia with a spiral-like appearance ("twisting of the points") and complexes that at first look positive and then negative on an electrocardiogram. It is precipitated by a long Q-T interval, which often is induced by drugs (quinidine, procainamide, or disopyramide) but which may be the result of hypokalemia, hypomagnesemia, or profound bradycardia. The first line of treatment is IV magnesium sulfate, as well as defibrillation if the patient is unstable. See also long QT syndrome.

torsades de pointes [tor-sahd´ duh pwahnt]
an atypical rapid ventricular tachycardia with periodic waxing and waning of amplitude of the QRS complexes on the electrocardiogram. It is usually drug related and may be either self-limiting or progressing to ventricular fibrillation.


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There was one case of confirmed and one case of possible Torsades de Pointes (TdP) in sertin-dole-treated patients, and none in risperidone patients; the confirmed case was in a 79-year-old woman, who was not on other medications that could have increased this risk, and who died a few days after TdP was detected, he said.
Although a link between the use of typical anti-psychotic drugs and both torsades de pointes (a form of heart disorder) and sudden cardiac death has been established, this risk was thought to be lower with the use of atypical drugs," the authors wrote.
Although a link between the use of typical anti-psychotic drugs and both torsades de pointes (a form of heart disorder) and sudden cardiac death has been established, this risk was thought to be lower with the use of atypical drugs," the authors wrote.
 
 
 
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