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topoisomerase

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topoisomerase
[to′po-i′so-mer-ās]
an enzyme involved in mobilization and replication of DNA during cell division.

topoisomerase [to″po-i´so-mer-ās]
an enzyme involved in mobilization and replication of DNA during cell division.

topoisomerase
an enzyme involved in DNA replication that introduces a single-strand nick in the DNA enabling it to swivel and thereby relieve the accumulated winding strain generated during unwinding of the double helix.


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8), and more recently, the need for such an enzyme has been reiterated by those examining the actions of topoisomerase I inhibitors (9, 10).
9780879698799 Untangling the double helix; DNA entanglement and the action of the DNA topoisomerases.
Resistance is caused mainly by amino acid changes in quinolone resistance-determining regions (QRDRs) of the subunits of DNA topoisomerase IV (topo IV; [parC.
 
 
 
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