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Togaviridae |
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tocainide HCl (tōkā´nīd), n brand name: Tonocard; drug class: antidysrhythmic (Class IB), lidocaine analog; action: decreases sodium and potassium conductance, which decreases myocardial excitability; use: treatment of documented life-threatening ventricular dysrhythmias. Togaviridae n a family of enveloped, linear, nonsegmented RNA viruses with icosahedral symmetry, which includes the rubella and yellow fever viruses. Togaviridae a large family of viruses; presently two genera are defined: Alphavirus, which contains arthropod-borne viruses that cause eastern, western and Venezuelan encephalitis, and Rubivirus, which contains rubella virus of humans and is not arthropod-borne. Members of both genera have similar physicochemical properties. They are enveloped (toga = cloak) about 60 nm diameter, contain a single-stranded, plus sense RNA genome, replicate in the cytoplasm of cells and mature by budding through cytoplasmic membranes. Flaviviruses, which are also arthropod-borne, were once included in the family, but are now a separate family, Flaviviridae. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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