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thioguanine |
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thioguanine /thio·gua·nine/ (-gwah´nēn) an antineoplastic derived from mercaptopurine; used in the treatment of acute myelogenous leukemia.
thioguanine [thī′ōgwä′nēn] a purine analog antagonist, an antineoplastic that acts as an antimetabolite. indications It is prescribed in the treatment of a variety of malignant neoplastic diseases, especially acute and chronic myelogenous leukemias. contraindications Known hypersensitivity or resistance to this drug prohibits its use. It is not given during pregnancy. adverse effects Among the most serious adverse effects are bone marrow depression, GI distress, and stomatitis. thioguanine [thi″o-gwah´nēn] a guanine analogue in which sulfur replaces the oxygen atom of guanine; used as an antineoplastic agent almost exclusively in the treatment of acute myelogenous leukemia and acute lymphoblastic leukemia. Called also 6-thioguanine and 6-TG.
thioguanine an antineoplastic (2-aminopurine-6-thiol) used in the treatment of leukemia.
thioguanine Lanvis® Oncology An antimitotic purine analogue, used against AML. See Purine. Want to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit the webmaster's page for free fun content. |
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