thioguanine

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Related to Tioguanine: thioguanine, Lanvis, 6-TG

thioguanine

 [thi″o-gwah´nēn]
a guanine analogue in which sulfur replaces the oxygen atom of guanine; used as an antineoplastic agent almost exclusively in the treatment of acute myelogenous leukemia and acute lymphoblastic leukemia. Called also 6-thioguanine and 6-TG.

thioguanine

/thio·gua·nine/ (-gwah´nēn) an antineoplastic derived from mercaptopurine; used in the treatment of acute myelogenous leukemia.

thioguanine

[thī′ōgwä′nēn]
a purine analog antagonist, an antineoplastic that acts as an antimetabolite.
indications It is prescribed in the treatment of a variety of malignant neoplastic diseases, especially acute and chronic myelogenous leukemias.
contraindications Known hypersensitivity or resistance to this drug prohibits its use. It is not given during pregnancy.
adverse effects Among the most serious adverse effects are bone marrow depression, GI distress, and stomatitis.

thioguanine

Lanvis® Oncology An antimitotic purine analogue, used against AML. See Purine.

thioguanine

Tioguanine, a drug used in the treatment of acute myeloblastic leukaemia. A brand name is Lanvis.

thioguanine

an antineoplastic (2-aminopurine-6-thiol) used in the treatment of leukemia.