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tiludronate |
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tiludronate /ti·lu·dro·nate/ (ti-loo´drah-nāt) an inhibitor of bone resorption, used as the disodium salt in the treatment of osteitis deformans. tiludronate, a parathyroid agent (calcium regulator). indication It is used to treat Paget's disease. contraindications Factors that prohibit its use include known hypersensitivity to biphosphonates, pathologic fractures, colitis, and severe renal disease with creatinine 5 mg/dL. Its use is also contraindicated in children. adverse effects Adverse effects include dry mouth, gastritis, vomiting, flatulence, gastric ulcers, rhinitis, rales, sinusitis, upper respiratory infection, headache, somnolence, dizziness, anxiety, vertigo, nervousness, involuntary movements, hyperparathyroidism, rash, epidermal necrosis, pruritus, sweating, nephrotoxicity, decreased mineralization of nonaffected bones, and pathologic fractures. Common side effects include nausea, diarrhea, and bone pain. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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