thromboxane (redirected from Thromboxanes)

thromboxane /throm·box·ane/ (-bok´san) either of two compounds, one designated A2 and the other B2. Thromboxane A2 is synthesized by platelets and is an inducer of platelet aggregation and platelet release functions and is a vasoconstrictor; it is very unstable and is hydrolyzed to thromboxane B2.

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throm·box·ane (thrm-bksn)

n.

Any of several compounds, originally derived from prostaglandin precursors in platelets, that stimulate aggregation of platelets and constriction of blood vessels.

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thromboxane (thrôm·bôkˑ·sān),

n one of a pair of compounds that effectively induces platelet aggregation.

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thromboxane

an intermediate in the metabolic pathway of arachidonic acid, formed from prostaglandin endoperoxides, and released from suitably stimulated platelets; the unstable form, thromboxane A₂, is a potent inducer of platelet aggregation and constrictor of arterial smooth muscle.