Cyclin D1 regulates cellular migration through the inhibition of thrombospondin 1
and ROCK signaling.
Plasma thrombospondin 1
as a predictor of postoperative liver dysfunction.
sup] showed that CD133(+) bone marrow-derived stem cells induced proliferation of endometrial surrounding cells through paracrine molecules such as thrombospondin 1
and insulin-like growth factor 1.
1] , GP1b[alpha] , vitronectin , and thrombospondin 1
Additional promising biomarkers for the early diagnosis and management of CI-AKI may be the cysteine rich protein 61 (CYR61), induced in the kidney within one hour after ischemic/toxic injury and detectable in the urine 3-6 hours later , KrUppel-like factor 6 (Zf9), a KrUppel-like transcription factor involved in the regulation of a number of downstream targets , thrombospondin 1
(TSP-1), a p53-dependent proapoptotic and antiangiogenic molecule , and IL-18, a proinflammatory cytokine that is known to be induced and cleaved in the proximal tubule and subsequently easily detected in the urine following ischemic AKI in animal models .
, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy.
03 in 17 chromosome 1 [Q09760] AA080628 phosphoribosylformylglycin amidine 7 synthase [P35421] AA080629 ORF 1130 [U20247] 6 AA080630 human thrombospondin 1
precursor 7 [P07996] AA080632 URP5 [1204259B] 16 AA080631 ERCC5 [D16305] 6 AA080635 murine erythroleukemia cardiac calcium 5 channel [U17869] AA080637 ORF gene product [X95373] 7 AA080638 latent transforming growth factor 8 beta-binding protein 3 precursor [A57293] AA080641 aminopeptidase [U35646] 28 AA080643 TO8A11.
11-16) Interestingly, an abnormal stromal-epithelial interaction, with increased expression of messenger RNA for vascular endothelial growth factor, fibronectin, thrombospondin 1
, and other factors involved in the formation of vascular stroma, and analogous to that noted in wound healing responses, has been reported in radial scars.
Example: Thrombospondin 1
(TSP1); kallikreins 2, 3, 5, and 11; and early prostate cancer antigen-2 (EPCA-2) were no go for further validation studies after they failed in a blinded test on an EDRN prostate cancer reference set.
In the NG-treated platelets, there were increase in the levels of growth factor receptor-bound protein 2 (Grb2), thrombospondin 1
, tubulin alpha 6 and decrease in the levels of thioredoxin, Cu-Zn superoxide dismutase, DJ-1 protein, peroxiredoxin 3, thioredoxin-like protein 2, ribonuclease inhibitor, potassium channel subfamily V member 2, myosin regulatory light chain 9 and laminin receptor 1.
The markers approved for prevalidation were human kallikrein 2 (hk2), hk4, hk11, thrombospondin 1
, percent [-2]proPSA, and EPCA2 (early prostate-specific antigen 2).
Angiogenic macrophages produce the angiogenesis inhibitor thrombospondin 1