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thiamine
(redirected from Thiamine metabolism)

   Also found in: Encyclopedia, Wikipedia, Hutchinson 0.01 sec.
thiamine /thi·a·mine/ (thi´ah-min) vitamin B1; a water-soluble component of the B vitamin complex, found particularly in pork, organ meats, legumes, nuts, and whole grain or enriched breads and cereals. The active form is thiamine pyrophosphate (TPP), which serves as a coenzyme in various reactions. Deficiency can result in beriberi and is a factor in alcoholic neuritis and Wernicke-Korsakoff syndrome. Written also thiamin.
thiamine pyrophosphate  (TPP) the active form of thiamine, serving as a coenzyme in a variety of reactions, particularly in carbohydrate metabolism.

thi·a·mine (th-mn, -mn) or thi·a·min (-mn)
n.
A vitamin of the vitamin B complex, found in meat, yeast, and the bran coat of grains, and necessary for carbohydrate metabolism and normal neural activity. Also called vitamin B1.

Thiamine
A B vitamin essential for the body to process carbohydrates and fats. Alcoholics may suffer complications (including Wernike-Korsakoff syndrome) from a deficiency of this vitamin.

thiamine
[thī′əmin]
Etymology: Gk, theion, containing sulfur, amine, ammonia
a water-soluble, crystalline compound of the B vitamin complex, essential for normal metabolism and health of the cardiovascular and nervous systems. Thiamine plays a key role in the metabolic breakdown of glucose to yield energy in body tissues. Rich sources are pork; organ meats; green leafy vegetables; legumes; sweet corn; egg yolk; cornmeal; brown rice; yeast; and the germ and husks of grains, berries, and nuts. It is not stored in the body and must be supplied daily. A deficiency of thiamine affects chiefly the nervous system, the circulation, and the GI tract. Symptoms include irritability, emotional disturbances, loss of appetite, multiple neuritis, increased pulse rate, dyspnea, reduced intestinal motility, and heart irregularities. Severe deficiency causes beriberi. Also spelled thiamin. Also called antiberiberi factor, antineuritic vitamin, vitamin B1.

thiamine,
n See vitamin B1.

thiamin, thiamine
vitamin B1; a component of the B complex group of vitamins, found in various foodstuffs and present in the free state in blood plasma and cerebrospinal fluid. The pharmaceutical products are thiamin hydrochloride and thiamin pyrophosphate.

thiamin nutritional deficiency
an unlikely event in food animals with two exceptions: the secondary deficiency caused in horses and pigs by thiaminase in bracken and the primary deficiency in horses fed a diet almost entirely of turnips. In companion animals, the deficiency is much more common. Dogs, and particularly cats, fed diets in which thiamin has been destroyed, usually by excessive heat in processing but also by the inclusion of raw fish of certain marine species or sulfur dioxide as a food preservative, will develop signs of deficiency which include ataxia, mydriasis and convulsions.


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