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Th cell

   Also found in: Wikipedia 0.02 sec.
Th cell
helper T lymphocyte.


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Instruction of different Th cell fates via different transcription factors, such as T-bet for Th1 cells and GATA-3 for Th2 cells has been demonstrated in several mouse models and some evidence has been shown for human diseases (46,47).
Also, an imbalance in the relative numbers or/and activity of these Th cell subpopulations may affect the state and progression of several diseases, including infectious, allergic and auto-immune disorders, but also cancer (Clerici et al.
Each Treg has a gene turned on that is also turned on in the corresponding Th cell, and each Treg appears to be produced in greater numbers when its corresponding Th cell responds to an intruder.
 
 
 
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