tetrahydrofolic acid

(redirected from Tetrahydrofolates)
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tet·ra·hy·dro·fo·lic ac·id (FH4),

(tet'ră-hī'drō-fō'lik as'id),
The active coenzyme form of folic acid; participates in one-carbon metabolism.
Synonym(s): coenzyme C, coenzyme F

tetrahydrofolic acid

/tet·ra·hy·dro·fo·lic ac·id/ (-hi″dro-fo´lik) a form of folic acid in which the pteridine ring is fully reduced; it is the parent compound of a variety of coenzymes that serve as carriers of one-carbon groups in metabolic reactions; in dissociated form, called tetrahydrofolate. Abbreviated THF.

tet·ra·hy·dro·fo·lic ac·id

(THFA) (tet'ră-hī-drŏ-fō'lik as'id)
The active form of folic acid, which can donate four formyl groups during DNA synthesis.
References in periodicals archive ?
With the preferred substrate tetrahydrofolate (THF), [1] glutamate chain-length elongation is rapid up to a glutamate chain length of five glutamate residues.
Moreover, the T allele of the MTHFR gene has been associated with an accumulation of formylated tetrahydrofolate in red blood cells, which is not the normal form of RCF (12).