Testosterone

testosterone /tes·tos·te·rone/ (tes-tos´te-ron?) the principal androgenic hormone, produced by the interstitial (Leydig) cells of the testes in response to stimulation by the luteinizing hormone of the anterior pituitary gland; it is thought to be responsible for regulation of gonadotropic secretion, spermatogenesis, and wolffian duct differentiation. It is also responsible for other male characteristics after its conversion to dihydrotestosterone. In addition, testosterone possesses protein anabolic properties. It is used as replacement therapy for androgen deficiency in males, in the treatment of delayed male puberty or hypogonadism, and in the palliation of certain breast cancers in females; used as the base or various esters (e.g., cypionate, enanthate, propionate).

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tes·tos·ter·one (ts-tst-rn)

n.

A steroid hormone and the most potent naturally occurring androgen that is formed by the interstitial cells of the testes, and possibly by the ovary and adrenal cortex, may be produced in nonglandular tissues from precursors such as androstenedione, and is used in the treatment of hypogonadism, cryptorchism, carcinomas, and menorrhagia.

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Testosterone

Male hormone produced by the testes and (in small amounts) in the ovaries. Testosterone is responsible for some masculine secondary sex characteristics such as growth of body hair and deepening voice.

Mentioned in: Anabolic Steroid Use, Hormone Replacement Therapy, Klinefelter Syndrome, Menopause, Saw Palmetto

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testosterone

the most important male sex hormone (androgen) produced by the Leydig cells of the testes in response to luteinizing hormone (LH) secreted by the pituitary. Its chief function is to stimulate the development of the male reproductive organs and the secondary sex characters, such as the crest. It is necessary for the appearance of normal male sexual behavior. It encourages growth of bone and muscle, and helps maintain muscle strength. It is occasionally secreted in large amounts also by granulosa-theca cell tumors of the ovary, especially in mares.

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testosterone cyclopentylpropionate, testosterone cypionate, testosterone propionate

esters with a long period of activity.

testosterone-responsive dermatosis

a bilaterally symmetrical alopecia, primarily affecting the flanks, ventral abdomen and caudomedial aspect of the thighs of male dogs. The cause is believed to be hypotestosteronism.