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testicular feminization

   Also found in: Dictionary/thesaurus, Acronyms, Wikipedia 0.03 sec.
feminization /fem·i·ni·za·tion/ (fem″ĭ-nĭ-za´shun)
1. the normal development of primary and secondary sex characters in females.
2. the induction or development of female secondary sex characters in the male.

testicular feminization  complete androgen resistance.

testicular feminization.
feminization
1. the normal induction or development of female sex characters.
2. the induction or development of female secondary sex characters in the male, e.g. in testicular sertoli cell tumor.

testicular feminization
a condition in which the subject is phenotypically female, but lacks nuclear sex chromatin and is of XY chromosomal sex.

testicular feminization
Androgen-insensitivity syndrome, feminization; Morris syndrome Endocrinology An X-linked pseudohermaphroditic state occurring in a genotypic XY ♂ with a ♀ phenotype; there is normal secretion of and response to müllerian inhibiting hormone, resulting in a phenotypic ♀ Clinical ♀ habitus, sexual behavior and 2º sex characteristics, associated with a blind vaginal pouch without uterine tissue, scanty pubic and axillary hair, and internally, undescended testicles; although the gonads often harbor Sertoli cell adenomas, malignancy occurs in 4% of TF Lab Normal testosterone levels. See Male pseudohermaphroditism.


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