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Teardrop Cell

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Teardrop Cell
A deformed RBC which is tugged to a nipple at one end, having squeezed through a reticuloendothelial system with increased connective tissue
Aetiology Myelofibrosis, and other reticuloendothelial replacement disorders that compromise the bone marrow space, causing splenic overload or decreased functional splenic tissue—e.g., megaloblastic anaemia, hereditary elliptocytosis, anaemia of renal disease, haemolytic anaemias, sickle cell anaemia, thalassemia, and bone marrow infiltration by haematologic and non-haematologic malignancies may also be accompanied by dacrocytosis. Tear drop cells are also seen in normal peripheral blood smears as an artefact of slide preparation; such dacrocytes are usually easily recognised as their 'tails' all point in the same direction


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Notably, the presence of spherocytes (hemolysis), teardrop cells (myelofibrosis, bone marrow metastases), or sickle cells (sickle-cell anemia), as examples, give information beyond that of the standard indices.
 
 
 
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