Taxol


Also found in: Dictionary, Encyclopedia, Wikipedia.

Taxol

 [tak´sol]
trademark for a preparation of paclitaxel, an antineoplastic agent.

Taxol

(tăk′sôl′)
A trademark for the drug paclitaxel.

Taxol

a trademark for an anticancer drug (paclitaxel).

Taxol®

Paclitaxel Oncology A chemotherapeutic used to manage Pts with ovarian, breast CAs, non-small cell lung CA, melanoma, KS who are not candidates for potentially curative surgery and/or RT Mechanism Taxol blocks mitosis by stabilizing microtubules and promoting tubulin polymerization, resulting in non-functional microtubules. See Ovarian cancer.

Taxol

A brand name for PACLITAXEL.

Patient discussion about Taxol

Q. How you guys have coped with the side effect of taxol. I was given Taxol after a long and heavy round of chemotherapy and was told that it will be an easy and safe drug when compared to the drugs that I have taken before …but I had severe allergic reactions for some months I think it may be a year with one being very serious that required antihistamines, with having oxygen and caused such pain in my back that I understood the highest level of discomfort. I don’t know how you guys have coped with the side effect of taxol ….I have experienced the worst possible pain in my life which cannot even come with the surgery…..but one thing I found that I was cured at least for god`s sake..

A. chemotherapy sux...i myself didn't have to go through that, but had to see someone very dear to me go through that. she went through very difficult time but survived and thank god it has been at least 2 years since and she is fine. it was frustrating to sit there not being able to do anything about it. but you should know-
it's temporary, and god's will - you'll come out of it triumphant!

Q. After Taxol/Carbo, then Alimta, treatments stopped because tumors no longer shrinking. Anything else to try? I was diagnosed with Stage 3 lung cancer about 6 months ago. Because of the weakness of my lungs due to advanced COPD, the Oncologist ruled out surgery & radiation so Chemo was the only alternative. I am now under Hospice care.

A. this is a question that the oncologist should answer...there are a lot of chemo treatments out there- but not always firring to the type of lung caner. but i'm sure he would suggest them...
look- there's some treatments in clinical trials. check them out maybe there'll be something for you. look under the topic "research":
http://www.nlm.nih.gov/medlineplus/lungcancer.html#cat27

More discussions about Taxol
References in periodicals archive ?
La tecnica del cultivo de tejidos vegetales in vitro es una herramienta exitosa para la generacion de cultivos de callos y celulas que produzcan metabolitos secundarios de gran importancia farmaceutica tales como el taxol y taxoides relacionados, sin que se destruyan los arboles de Taxus spp.
After Taxol treatment, the axonal endings now resemble growth cones and are better able to push through the inhibitory, environmental gauntlet characteristic of the injury-site scar.
For example, many protist and fungal tubulins are only slightly affected by taxol (5).
The scientists report that Taxol promotes regeneration of injured CNS-nerve cells in two ways: Taxol stabilizes the microtubules so that their order is maintained and the injured nerve cells regain their ability to grow.
coli to produce precursor of Taxol and this bacteria can produce 1,000 times more of these precursors than any other engineered microbe," Dr Ajikumar said in an e- mail interview from Massachusetts Institute of Technology where he is a post doctoral associate in the department of chemical engineering.
Sacks and MOG admitted that Taxol caused the injury to the patient through infiltration, which resulted in the patient developing cellulitis and skin breakdown necessitating multiple hospital stays.
Robert Holton at Florida State University were working on creating a totally synthetic form of Bacatin III and Taxol.
Bio-pharmaceutical maker Bioxel Pharma, a leading Quebec manufacturer of Taxol, has a $15,000 interest in the Algoma yew plantation.
NIH's partnership with BMS provided the company with the research results that enabled Taxol to be commercialized quickly and made available as a treatment for cancer patients.
Similar action occurred last June when an equal number of states charged the company with blocking a generic version of Taxol, a cancer-fighting medication.
Now comes a thirty-two state lawsuit against Bristol Meyers-Squibb for allegedly violating federal and state antitrust laws by fraudulently securing patents for the anti-cancer drug Taxol and illegally manipulating regulatory and judicial proceedings.
Taxol, made from Yew bark extract, was recommended as part of initial chemotherapy for people with advanced non-small-cell lung cancer.