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cimetidine |
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cimetidine /ci·met·i·dine/ (si-met´i-den) a histamine H2 receptor antagonist, which inhibits gastric acid secretion; used as the base or the monohydrochloride salt in the treatment and prophylaxis of gastric or duodenal ulcers, gastroesophageal reflux disease, upper gastrointestinal bleeding, and conditions associated with gastric hypersecretion.
cimetidine (simet´idēn´), n brand names: Tagamet, Apo-Cimetidine; drug class: H2-histamine receptor antagonist; action: inhibits histamine at H2-histamine receptor site in parietal cells, which inhibits gastric acid secretion; uses: short-term treatment of duodenal and gastric ulcers by the control of hyperacidity. cimetidine a histamine H2-receptor antagonist that inhibits the action of histamine at cell surface receptors of the gastric parietal cells and reduces basal gastric acid secretion and secretion stimulated by food, histamine, gastrin and insulin. It is used for short-term treatment of peptic ulcer and for treatment of pathological hypersecretory conditions. |
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