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TMP-SMX

   Also found in: Acronyms 0.01 sec.
Trimethoprim-sulfamethoxazole (TMP-SMX)
An antibiotic used to treat and prevent PCP.

TMP-SMX,
n acronym for trimethoprim-sulfamethoxazole.

TMP-SMX
Trimethoprim-sulfamethoxazole, Bactrim, Septra AIDS A drug combination used for PCP pneumonia, toxoplasmosis as well Adverse effects Allergies, fever, itchy rash, N&V, neutropenia. See AIDS.


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First-line treatment for acute human melioidosis is intravenous ceftazidime or a carbapenem for at least 10-14 days, followed by oral TMP-SMX with or without doxycycline for 12-20 weeks (3,6).
The mainstay of treatment for patients with CGD is prophylactic antimicrobial or antifungal therapy; TMP-SMX, clotrimazole, and itraconazole are the most commonly used.
As doxycycline is generally not recommended for pregnant women, we assumed a PEP dosage of 160 mg/800 mg TMP-SMX 2x/day for the duration of the pregnancy, starting 8-12 days postexposure (21).
 
 
 
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