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a factor occurring in sensitized lymphocytes that has the capacity to transfer delayed hypersensitivity to a normal (nonreactive) individual. It confers cell-mediated immunity and therefore has been found to be useful in treating conditions in which there is a disorder of immune response. As an adjunct to antibiotic therapy it is useful in the treatment of such antibiotic-resistant diseases as candidiasis, coccidioidomycosis, and leprosy.
abbreviation for transfer factor.
T geneA genes on chromosome 6q27 that encodes brachyury, an embryonic nuclear transcription factor that effects transcription of genes required for mesoderm formation and differentiation, and mediates epithelial-mesenchymal transition. It is localised to notochord-derived cells.
Brachyury is the definitive diagnostic marker of chordoma; it is overexpressed in various cancers and promotes invasion.
Abbreviation for tuning fork.