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TD50

   Also found in: Acronyms 0.01 sec.
TD50 median toxic dose.
TD50
Toxic dose, see there


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When administered at higher doses in the rat, (125, 250, 500 and 750 mg/kg), the TD50 was 470 mg/kg, suggesting that the compound does not produce relevant sedative and motor deficit effects, having a very high therapeutic index (TI = TD50/ED50 = 783) as measured in the rat pain models.
 
 
 
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