TAS1R3

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TAS1R3

A gene on chromosome 1p36.33 that encodes a G protein-coupled receptor which acts a putative taste receptor: TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate); TAS1R2/TAS1R3 recognises diverse natural and synthetic sweeteners.
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Identification of the cyclamate interaction site within the transmembrane domain of the human sweet taste receptor subunit T1R3.
El gusto o desagrado por un sabor en particular puede inducirse manipulando ciertos genes: se sabe que existen 5 sabores basicos, que se reconocen mediante los receptores celulares de la lengua, los cuales dependen a su vez de 3 genes, T1R1, T1R2 y T1R3.
Mice and humans have a similar genetic makeup, so scientists were able to pinpoint the corresponding human gene, called T1R3.