TAS1R1

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TAS1R1

A gene on chromosome 1p36.13 that encodes a G protein-coupled receptor which acts as a putative taste receptor: TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate).
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Two further cell lines, designated T1R1 and T1R2, and four other cell lines, designated T4R1-T4R4, were established from the T1- and T4-induced tumors, respectively.
El gusto o desagrado por un sabor en particular puede inducirse manipulando ciertos genes: se sabe que existen 5 sabores basicos, que se reconocen mediante los receptores celulares de la lengua, los cuales dependen a su vez de 3 genes, T1R1, T1R2 y T1R3.
The researchers also discovered that the T1R1 gene, which encodes a key receptor for the savoury or 'umami' flavour of meat, has become an inactive 'pseudogene' due to two mutations.