T-cell receptor

(redirected from T-lymphocyte antigen receptor)
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T-cell re·cep·tor

(TCR) (sel rĕ-sep'tŏr)
An adhesion molecule on the membrane of T lymphocytes, which serves as the receptor for antigen bound to antigen-presenting cells (APC) through MHC molecules. It is expressed in a complex with CD3. It is in proximity to the MHC-restricted receptor (CD4 or CD8).
Synonym(s): T-lymphocyte antigen receptor.

T-cell receptor

Abbreviation: TCR
One of two polypeptide chains (a or ß) on the surface of T lymphocytes that recognize and bind foreign antigens. TCRs are antigen specific; their activity depends on antigen processing by macrophages or other antigen-presenting cells and the presence of major histocompatibility complex proteins to which peptides from the antigen are bound.
See: autoimmunity; immune response; T cell
See also: receptor