T-cell lymphoma

lymphoma (limfō´m),

n a neoplasm made up of lymphoid tissue.

lymphoma, B-cell,

n a group of heterogenous lymphoid tumors generally expressing one or more B-cell antigens or representing malignant transformations of B lymphocytes.

lymphoma, Burkitt,

n a type of B-cell lymphoma suspected to be related to infection by the Epstein-Barr virus (EBV). The classical (African) variation usually affects the bowels, whereas the endemic variation affects the jaws.

lymphoma, Hodgkin,

n a group of malignant B-cell lymphomas suspected of being related to the Epstein-Barr virus. Characterized by the presence of Reed-Sternberg cells.

lymphoma, MALT,

n a type of lymphoid tumor that can occur in any mucous tissue and in salivary glands. These tumors arise from benign lymphoepithelial lesions.

lymphoma, non-Hodgkin,

n a group of malignant tumors of a lymphoid tissue that differ from Hodgkin disease, being more heterogeneous with respect to malignant cell lineage, clinical course, prognosis, and therapy. The only feature shared by these tumors is the absence of Reed-Sternberg cells, which are characteristic of Hodgkin disease.

lymphoma, T-cell,

n an adult T-cell leukemia; an acute or chronic disease associated with a human T-cell virus, with lymphadenopathy, hepatosplenomegaly, skin lesions, peripheral blood involvement, and hypercalcemia.

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T-cell lymphoma

A malignant proliferation of T cells arising in the skin, diagnosed by detecting rearrangement of the T-cell receptor's β chain; TCLs are often 'driven' by EBV and other viral infections; 90% of all Pts with TCL have extracutaneous involvement when diagnosed. See Mycosis fungoides.

T-cell lymphomas

Small lymphocytic (well-differentiated lymphocyte-like) lymphoma–13%

Convoluted cell lymphoma or poorly-differentiated lymphocytic lymphoma–52%

Immunoblastic sarcoma or 'histiocytic' lymphoma–19%

Mycosis fungoides/Sézary syndrome–11%

Lymphoepithelial cell (Lennert's) lymphoma–5%

Cutaneous T-cell lymphoma

HTLV (I, II)–induced lymphoma