T cell-rich B-cell lymphoma

T cell-rich B-cell lymphoma

monoclonal B-cell lymphoma that contains abundant reactive T cells; more than 90% of the cells are of T-cell origin, masking the large cells that form the neoplastic B-cell component.
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False negatives may emerge because of low-quality DNA or a low-level clonal population (<1%) admixed within a reactive inflammatory background, for example, T cell-rich B-cell lymphoma and Hodgkin lymphoma.
Angiocentric destruction observed in some forms of EBV-related, T cell-rich B-cell lymphoma (lymphomatoid granulomatosis) is not a common feature in pyothorax-associated lymphoma.
Pathologically it is best classified as an EBV-induced T cell-rich B-cell lymphoma.