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synaptic plasticity
(redirected from Synaptic efficacy)

   Also found in: Wikipedia 0.01 sec.
synaptic plasticity
 Physiology Malleability present in synapses in various forms–eg, presynaptic inhibition, homosynaptic depression, presynaptic facilitation and modulation of transmitter release by tonic depolarization of sensory neuron. See Neuroplasticity, Nitric oxide.


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In the mature nervous system, Glu is pivotal in neuroplasticity, in which there are use-dependent changes in synaptic efficacy as well as alterations in synaptic structure (Tsai et al, 1995; Kristensen et al, 1993, Scimemi et al, 2005).
Long-term potentiation (LTP) is a widely used paradigm for increasing synaptic efficacy, and the induction of one form of LTP requires the activation of NMDA receptors (Collingride and Daries, 1989).
 
 
 
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