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sympatholytic
(redirected from Sympatholytics)

   Also found in: Dictionary/thesaurus, Encyclopedia, Wikipedia 0.01 sec.
sympatholytic /sym·pa·tho·lyt·ic/ (-lit´ik)
1. antiadrenergic; opposing the effects of impulses conveyed by adrenergic postganglionic fibers of the sympathetic nervous system.
2. an agent that so acts.

sym·pa·tho·lyt·ic (smp-th-ltk)
adj.
Opposing the physiological effects caused by stimulation of the sympathetic nervous system.

sympatholytic, sympatholytic agent.
sympatholytic [sim″pah-tho-lit´ik]
1. blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion.
2. an agent that produces such an effect; called also antiadrenergic.

sympatholytic (sim´pthōlit´ik),
adj pertaining to a drug that blocks the effects of stimulation of the sympathetic nervous system. See also adrenolytic.

sympatholytic
antiadrenergic: blocking transmission of impulses from the adrenergic (sympathetic) postganglionic fibers to effector organs or tissues, inhibiting such sympathetic functions as smooth muscle contraction and glandular secretion. Also, an agent that produces such an effect.


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The sympatholytics are also recommended because they block the peripheral autonomic hyperarousal in PTSD, but they can also cause troublesome side effects, including hypotension.
64) Central [alpha]-2 agonists (clonidine) may cause peripheral vasoconstriction via crossover stimulation of peripheral postsynaptic [alpha]-1 receptors, (65) while sympatholytics such as methyldopa (66) may cause transient hypertensive exacerbation before their hypotensive effects become manifest.
Hypotension with a relative bradycardia could be due to sympatholytics (think of beta-blockers, opiates), membrane depressants (think of quinidine, tricyclics) and others (think of fluoride, organophosphates, sedative-hypnotics).
 
 
 
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