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swainsonine

   Also found in: Wikipedia 0.01 sec.
swainsonine
a trihydroxylated indolizidine alkaloid found in Swainsona spp., Schizoctonia leguminicola and Astragalus spp. It is a potent α-mannosidase inhibitor and poisoning by it leads to accumulation of mannosidose in tissues.


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Trop Med and Int Health 5: 418-422 Rooprai HK, Kandanearatchi A, Maidment SL, Christidou M, Trillo-Pazos G, Dexter DT, Rucklidge GJ, Widmer W, Pilkington GJ (2001) Evaluation of the effects of swainsonine, captopril, tangeretin and nobiletin on the biological behavior of brain tumor cells in vitro.
 
 
 
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