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surrogate marker
(redirected from Surrogate endpoint)

   Also found in: Acronyms, Wikipedia 0.01 sec.
surrogate marker
Lab medicine A parameter or measured to detect a pathologic condition when a more specific test doesn't exist, is impractical or not cost-effective; surrogate testing has been used for non-A, non-B hepatitis, measuring ALT and antibodies to HBV core antigen–anti-HBc and HC


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A concluding section addresses research trends for the future such as surrogate endpoints and registries.
In oncology, a reduction in tumour size is suggested as an appropriate surrogate endpoint to assess potential treatments that may improve survival rates in this patient population.
Zevalin is also indicated, under accelerated approval, for the treatment of relapsed or refractory, rituximab-naive, low-grade and follicular NHL based on studies using a surrogate endpoint of overall response rate.
 
 
 
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