surfactant replacement therapy

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Neonatology Intratracheally administered bronchoalveolar fluid derived from calves–98% lipids, comprised of 90% phospholipid, especially dipalmitoyl-phosphatidylcholine and 2% apoproteins, which markedly improves gas exchange in premature infants; prophylactic bovine surfactant administered intratracheally ↓ need for neonatal respiratory support and ↑ survival of premature infants, especially < 30 wks. See Hyaline membrane disease.

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