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supercoiling

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
supercoiling,
the underwinding or overwinding of a DNA helix. See also DNA gyrase.


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These enzymes control the degree of supercoiling and are required for undoing knots and tangles in the genetic material.
Any breaks present in the DNA cause the supercoiling to relax locally, and negatively charged loops of DNA are then free to extend and migrate in the electric field toward the anode as a "comet tail.
 
 
 
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