sulfinpyrazone /sul·fin·py·ra·zone/ (sul″fin-pi´rah-zōn) a uricosuric agent used in the treatment of gout.
Sulfinpyrazone
sulfinpyrazone
sulfinpyrazone [sul″fin-pi´rah-zōn]
sulfinpyrazone (sul´finpir´
zōn´),
Sulfinpyrazone
A drug that corrects hyperuricemia by increasing the urinary excretion of urate.
Mentioned in: Gout
sulfinpyrazone
[sul′finpir′əzōn]
a uricosuric drug.
indications It is prescribed in the treatment of chronic gout and intermittent gouty arthritis.
contraindications Peptic ulcer, ulcerative colitis, renal dysfunction, or known hypersensitivity to this drug or to phenylbutazone prohibits its use. It is not usually given during an acute attack of gout.
adverse effects Among the more serious adverse effects are GI ulcers, blood dyscrasias, and dermatitis.
sulfinpyrazone [sul″fin-pi´rah-zōn]
a uricosuric compound used in gout to promote excretion of uric acid; administered orally. It also prolongs platelet survival and inhibits platelet adherence to subendothelial cells and prostaglandin synthesis and has been studied as an antithrombotic agent.
sulfinpyrazone (sul´finpir´
zōn´),n brand name: Anturane;
drug class: uricosuric;
action: inhibits tubular reabsorption of urates, with increased excretion of uric acid; inhibits prostaglandin synthesis, which decreases platelet aggregation;
use: treatment of chronic gouty arthritis.
drug class: uricosuric;
action: inhibits tubular reabsorption of urates, with increased excretion of uric acid; inhibits prostaglandin synthesis, which decreases platelet aggregation;
use: treatment of chronic gouty arthritis.
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