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succinate
(redirected from Succinate dehydrogenase)

   Also found in: Dictionary/thesaurus, Acronyms, Encyclopedia, Wikipedia 0.01 sec.
succinate /suc·ci·nate/ (suk´sĭ-nāt) any salt or ester of succinic acid.
succinate semialdehyde  γ.

suc·ci·nate (sks-nt)
n.
A salt or ester of succinic acid.

succinate [suk´sĭ-nāt]
any salt, ester, or anionic form of succinic acid.

succinate
any salt of succinic acid.

succinate dehydrogenase
an enzyme of the TCA cycle, located in the inner mitochondrial membrane that splits off hydrogen from succinic acid.


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The capacity of classic markers for mitochondrial density, ie, the capacity of citrate synthase (CS) and succinate dehydrogenase (SDH), as well the capacity of cytochrome c oxidase (COX) and beta-hydroxyacyl-CoA dehydrogenase (HAD), was determined in homogenized muscle biopsy samples obtained from the vastus lateralis muscle of nonexercising healthy young (age 20 [+ or -] 2 yr) subjects (31 women, 7 men).
Our working hypothesis is that tryptamine inhibits succinate dehydrogenase (SDH), a Krebs cycle enzyme that converts succinate to fumerate ultimately increasing ATP levels.
A Qualitative and Quantitative Assessment in Muscle Succinate dehydrogenase (SDH) has frequently been used as a qualitative histochemical marker for the presence of "ragged-red fibers" in skeletal muscle, which indicates abnormally increased numbers of mitochondria; this defect also is detected by the modified Gomori trichrome stain.
 
 
 
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