| genetic marker n. A gene phenotypically associated with a particular, easily identified trait and used to identify an individual or cell carrying that gene. |
genetic marker,
any specific gene that produces a readily recognizable genetic trait that can be used in family and population studies or in linkage analysis. Also called gene marker, marker gene.
genetic [jĕ-net´ik]
1. pertaining to reproduction or to birth or origin.
2. inherited.
genetic code the arrangement of nucleotides in the polynucleotide chain of a chromosome; it governs the transmission of genetic information to proteins, i.e., determines the sequence of amino acids in the polypeptide chain making up each protein synthesized by the cell. Genetic information is coded in DNA by means of four bases: two purines (adenine and guanine) and two pyrimidines (thymine and cystosine). Each adjacent sequence of three bases (a codon) determines the insertion of a specific amino acid. In RNA, uracil replaces thymine.
genetic map
1. the location of mutations along the length of a chromosome, as determined by recombination experiments. The unit of length is the centimorgan (cM), one crossover per meiosis.
2. the sequence of base pairs along the DNA of a chromosome, a technique being applied to humans.
A gene map of Chromosome 18. From Copstead, 1996.
genetic marker a gene having alleles that are all expressed in the phenotype, that is, they are codominant, and which can be used to study inheritance. The various blood group systems and serum or red blood cell proteins easily detected by electrophoresis or immunodiffusion are commonly used markers.
genetic marker,
n a specific gene that produces a readily recognizable genetic trait that can be used in family and population studies or in linkage analysis.
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