strychnine /strych·nine/ (strik´nīn) a very poisonous alkaloid, obtained chiefly from Strychnos nux-vomica and other species of Strychnos, which causes excitation of all portions of the central nervous system by blocking postsynaptic inhibition of neural impulses.
strychnine
strychnine
strych·nine (str k n n , -nn, -n n)n. An extremely poisonous white crystalline alkaloid used as a poison for rodents and formerly used topically as a central nervous system stimulant. |
strychnine
[strik′nin, strik′nīn]
Etymology: Gr, strychnos, nightshade
a white crystalline alkaloid obtained from the leaves of the Strychnos nux-vomica plant. It is extremely toxic to the central nervous system, producing as a classic strychnine poisoning symptom an arched back (opisthotonus).
strychnine
a very poisonous alkaloid from seeds of the plant Strychnos nux-vomica and other species of Strychnos. A commonly used compound in malicious poisoning of dogs and used as a feral animal bait to which domestic dogs find access. The dogs may also be poisoned by eating the vermin. Clinical findings include tetanic convulsions especially in response to external stimuli.
strychnine
Toxicology A highly toxic alkaloid from Strychnos nux-vomica, commonly used as a rodenticide, that elicits CNS hyperactivity, causing painful, recurrent tonic seizures, muscle tightness, cramping, risus sardonicus, marked
flaccidity, decorticate posturing and death; Sx appear at 15 mg, death occurs with doses > 60 mg Management Control seizures with diazepam and phenobarbital; for muscle relaxation, curare, succinylcholine
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