streptogramins

streptogramins

Antibiotic drugs used to treat hospital-acquired infections when no other antibiotic is effective. Examples are quinupristin (Synercid), dalfoprisyin (Synercid), pristinamycin and virginiamycin.
References in periodicals archive ?
00; Lot 4 - antibiotics (sulfonamides, trimethoprim, Macrolides, linkozamidy and streptogramins, Aminoglycosides, Antibacterial agents from the group of quinoline, other bacterial agents (glycopeptide antibiotics) imidazole derivatives; Antibacterial agents for systemic use (derivatives nitrfuranu)) - 10/21/54 -00.
Molecular basis of resistance to macrolides, lincosamides and streptogramins in Staphylococcus saprophyticus clinical isolates.
Options: aminocyclitols, aminoglycosides, carbapenems, cephalosporins, monobactams, penicillins, cyclic lipopeptides, folate antagonists, fluoroquinolones, glycopeptides, immunomodulators, ketolides, lincosamides, macrocyclics, macrolides, mycobacterials, nitrofurans, oxazolidinones, peptides, pleuromutilins, polypeptides, pyridopyrimidines, quinolones, streptogramins, sulphonamides, tetracycline, other.
Because all erythromycin-resistant strains were also resistant to clindamycin (data not shown), we deduced the resistance mechanism to be resistance to macrolides, lincosamides, and streptogramins B system, as encoded by the erm genes (5).
Chloramphenicol, tetracyclines, macrolides, clindamycin and streptogramins.
Nonsense mutations in the lsa-like gene in Enterococcus faecalis isolates susceptible to lincosamides and streptogramins A.
The newer classes of streptogramins (Synercid[R]) and oxazolidinones (Zyvox[R]), both used to treat drug resistant staphylococcal infections, also work by inhibiting protein synthesis, as does the new ketolide, telethromycin (Bryskier, 2005c.
The macrolides, lincosamides, and streptogramins are three classes of antibiotics that are closely related in function but not structure.
Presented at the 4th International Conference on Macrolides, Azalides, Streptogramins and Ketulides; Jan.
In addition, group A streptogramins exert their effects in the early stages of protein synthesis, whereas group B streptogramins are active in the later stages (6, 7).
These fall into around thirty different groups, namely, aminocyclitols, aminoglycosides, beta lactams (carbapenems, cephalosporins (Generations 1-4), monobactams and penicillins), cyclic lipopeptides, folate antagonists, fluoroquinolones, glycopeptides, immunomodulators, ketolides, lincosamides, macrocyclics, macrolides, mycobacterials, nitrofurans, oxazolidinones, peptides, pleuromutilins, polypeptides, pyridopyrimidines, quinolones, streptogramins, sulphonamides and tetracycline and others.