orbital mixing underlie the bonding and structure issues of unsaturated compounds of heavy main-group elements, even though the substituent steric effects
are often the controlling factor of the geometry as shown in Section 1.
It can be presumed that the low degree of hydrolysis shown by the methylated starch could be due to the presence of methyl groups within the granules, hindering the enzyme-substrate interaction by steric effects
Researchers can no longer assume that steric effects
play the major role in determining stable forms, comments Weinhold.
The chelating of DNA with metal complexes will lead to the inhibition of DNA synthesis in cancer cells and microbes which result to apoptosis of the cell, this could be probably due to electronic effect, lipophilicitym steric effect
or could be to the hydrophobic behaviors to the molecule of the complex.
This might suggest that these solvents might be able to modify the dynamics of the PA66 interchain H-bonds, reducing their lifetime through steric effects
, thus provoking a further increase of PA66 amorphous phase molecular mobility.
Because we could not exclude the possibility that inhibition of complex formation by PSA-C2 and PSA-C4 is attributable to inhibition of PSA enzyme activity rather than to steric effects
, we measured the influence of antibodies on enzyme activity of free PSA (PSA activity index).
In a preliminary study (4) using a variety of dibasic acids, including hexahydrophthalic anhydride, anchimeric effects and steric effects
were investigated for oligoesters.
To account for steric effects
, we used NACCESS (37) to extract solvent-accessible surfaces (total, nonpolar, polar) from the final geometries.
He wondered whether steric effects
also would cause axial and equatorial hydrogen atoms of chair-shaped rings to have different chemical shifts.
Crosslinking, which is supposed to be a kind of chain entanglement, normally taking place in the noncrystalline phase and inducing the decrease in the crystallinity, is unconspicuous here due to molecule strain and steric effects
(37), The slight decrease of T sub.
Electron-donating and medium-sized steric effects
of secondary alkyl groups may contribute to the low self-hydrolysis.
6]-dependent enzymes; (2) the novel use of steric effects
as a general strategy to block processing of serine acyl enzyme intermediate and hence irreversibly inhibit serine proteinase targets such as elastase; (3) clinical trials of transglutaminase inhibitors as a treatment for acne; (4) the invention of quiescent affinity labels which has essentially revolutionized the affinity label concept.