Because the ASCUS to squamous intraepithelial lesion
ratio (ASCUS:SIL ratio) has much less variability than the ASCUS rate, this monitor is more useful for interlaboratory comparisons, such as in benchmarking.
A number of alternatives and enhancements for prospective rescreening have been proposed, including rapid prescreening/rescreening, enriching the random rescreen sample with known squamous intraepithelial lesion
(SIL) cases, 100% rescreening of NILM Pap tests, sharing cases among laboratories, and automated quality control slide selection.
ASC will consist of two types: those of undetermined significance (ASC-US) and those with cytologic changes suggestive of high-grade squamous intraepithelial lesions
(HSIL) that lack definitive criteria (ASC-H).
Atypical squamous cells, cannot exclude a high-grade squamous intraepithelial lesion
and its clinical significance in postmenopausal, pregnant, postpartum, and contraceptive-use patients.
At our institution, most high-grade squamous intraepithelial lesions
(HSILs) corresponding to cervical intraepithelial neoplasia (CIN) II and III are treated by loop electrosurgical excision procedure (LEEP).
Sherman ME, Schiffman M, Cox JT; Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesion
Triage Study Group.
Stoler MH, Schiffman M; Atypical Squamous Cells of Undetermined Significance-Low-grade Squamous Intraepithelial Lesion
Triage Study Group.
The result is presented using two reference threshold of: low threshold of cytology diagnosed squamous intraepithelial lesion
or high threshold of cytology diagnosed high grade intraepithelial lesion or worse lesion.
Immunohistochemical expression of granzyme B and vascular endothelial growth factor (VEGF) in normal uterine cervices and low and high grade squamous intraepithelial lesions
," European Journal Gynaecological Oncology, vol.
More than half of the women (55%) had a record of low-grade squamous intraepithelial lesions
(LSIL), which may develop into high-grade lesions and eventually result in cervical cancer.
Atypical squamous cells, cannot exclude high-grade squamous intraepithelial lesion
(ASC-H): a result not to be ignored.
In another study done by Khan and his colleagues the percentage of lowgrade squamous intraepithelial lesion