Squamous intraepithelial lesion

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squamous intraepithelial lesion

Cytology A term that encompasseses a spectrum of noninvasive cervical epithelial abnormalities–eg, flat condyloma, dysplasia/carcinoma in situ, CIN; the Bethesda Classification divides SILs into low-grade and high-grade lesions; the former encompass cellular changes associated with HPV cytopathic effect–koilocytotic atypia and mild dysplasia; high-grade lesions encompass moderate dysplasia, severe dysplasia, carcinoma in situ/CIN2–3. See CIN, High-grade squamous intraepithelial lesion, Low-grade squamous intraepithelial lesion, Pap smear.

Squamous intraepithelial lesion (SIL)

A term used to categorize the severity of abnormal changes arising in the squamous, or outermost, layer of the cervix.
Mentioned in: Cervical Cancer, Pap Test
References in periodicals archive ?
Consensus Statement 2: At a minimum, review all available slides for high-grade squamous intraepithelial lesion (HSIL) Pap tests with negative biopsies, with a correlation interval between 3 to 4 months but not exceeding 6 months.
Women 18-60 years old agreed to be followed over the course of the 5-year study to determine the main predictors of cytologic progression to squamous intraepithelial lesions (SIL) from ASCUS, Dr.
Atypical squamous cells, cannot exclude a high-grade squamous intraepithelial lesion and its clinical significance in postmenopausal, pregnant, postpartum, and contraceptive-use patients.
At our institution, most high-grade squamous intraepithelial lesions (HSILs) corresponding to cervical intraepithelial neoplasia (CIN) II and III are treated by loop electrosurgical excision procedure (LEEP).
Sherman ME, Schiffman M, Cox JT; Atypical Squamous Cells of Undetermined Significance/Low-Grade Squamous Intraepithelial Lesion Triage Study Group.
Unfortunately, the present testing and scoring paradigm does not use the current evidence-based paradigm in the screening, diagnosis, and follow-up of cervical neoplasia, particularly in the separation of low-grade squamous intraepithelial lesions (LSILs) and high-grade squamous intraepithelial lesions (HSILs).
Loop electrosurgical excision for high grade squamous intraepithelial lesion cervical cytology at Nakornping Hospital.
Concordance Rates for Target Diagnoses of Low-Grade Squamous Intraepithelial Lesion (LSIL), High-Grade Squamous Intraepithelial Lesion (HSIL), and Squamous Cell Carcinoma (SCC) by Year Target Diagnosis 2006 2007 LSIL concordance rate, 967 (79.
7) ASCUS = atypical squamous cells of undetermined significance; LSIL = low-grade squamous intraepithelial lesion; HSIL = high-grade squamous intraepithelial lesion.
high-grade squamous intraepithelial lesion or greater [HSIL+]) and histology (cervical intraepithelial neoplasia 2 or greater [CIN-2+]), in HIV-infected women (n = 420) and HIV-uninfected women (n = 279).
Comparison of the Bethesda and the British Society for Clinical Cytology (BSCC) classification systems for cervical cytology (8) Bethesda classification BSCC classification Negative for intraepithelial lesion or malignancy Negative Unsatisfactory for evaluation Inadequate Atypical squamous cells of undetermined Borderline significance (ASC-US) nuclear change Atypical squamous cells cannot exclude H-SIL (ASC-H) Atypical endocervical, endometrial or glandular cells (not otherwise specified or specify) Atypical endocervical or glandular cells favour neoplasia Low-grade squamous intraepithelial lesion (L-SIL) Mild dyskaryosis High-grade squamous intraepithelial lesion (H-SIL) Moderate dyskaryosis Severe dyskaryosis Squamous cell carcinoma Severe dyskaryosis ?