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A virus genus encompassing a poorly characterized group of retroviruses that cause vacuolation (foaming) of cultured cells; usually cause persistent but silent infections in their natural hosts and no diseases caused by these agents have been identified.


/Spu·ma·vi·rus/ (spu´mah-vi″rus) foamy viruses; a genus of nonpathogenic viruses of the subfamily Spumavirinae (family Retroviridae) that induce persistent infection in humans, primates, cats, cattle, and hamsters.


A genus of retroviruses occasionally transmitted to humans after exposure to the blood or body fluids of infected animals (e.g., apes, cats, or cattle).


a member of the subfamily Spumavirinae.
References in periodicals archive ?
Sequencing of the PCR products from one region indicated that the sequences from each worker were distinct from each other; however, all three demonstrated [is greater than] 80% homology to known spumavirus sequences of NHP origin.
Virus isolation was attempted by co-culturing the peripheral blood lymphocytes (PBLs) of worker 1 with a cell line known to be permissive for spumavirus infection.
Characterization of spumavirus infection in humans is limited.