Combined histologic patterns of a blue nevus, spindle and Spitz nevus
, or a deep penetrating nevus were identified in 40% of CMN.
Based on to the patient's history and clinical appearance, the differential diagnosis of the lesion included Spitz nevus
, as well as a lymphocytic infiltrate, lymphoma, or pseudolymphoma.
They revealed that PHH3 expression was higher in malignant melanomas, averaging 25/10HPF than in Spitz nevus
, averaging 0.
Lesions included adnexal neoplasm, ameloblastic fibro-odontoma, basal cell carcinoma, benign fibrous histiocytoma, blue nevus, chondrosarcoma, compound nevus, epithelioma adenoides cysticum, esthesioneuroblastoma, Ewing sarcoma, fibrosarcoma, giant cell granuloma, granulocytic sarcoma, hemangioma, hemangiopericytoma, Langerhans cell histiocytosis, lymphangioma, lymphoma, melanoma, neuroblastoma, neurofibroma, ossifying osteofibroma, osteochondroma, osteosarcoma, port wine stain, rhabdomyosarcoma, Spitz nevus
, and xanthogranuloma.
cogunlukla cocuk ve adolesanlarda gorulen, benin, genellikle edinsel melanositik tumordur.
The most common scenarios in melanoma litigation cases include nodular melanoma being misdiagnosed by a clinician or pathologist, a partial biopsy not capturing the most diagnostically relevant part of the lesion, malignant melanoma being misdiagnosed as a dysplastic or spitz nevus
, unrecognized desmoplastic malignant melanoma, and metastatic malignant melanoma with an unknown primary or recurrence of melanoma (Am.
Spitzoid lezyonlar, bir ucunda Spitz nevus
, diger ucunda ise Spitzoid melanom, arada ise atipik Spitz nevus
, atipik Spitzoid tumor veya malignite potansiyeli bilinmeyen Spitzoid tumor (Spitzoid tumor of uncertain malignant potential, STUMP) olarak degisik sekillerde isimlendirilen hem Spitz nevus
hem de melanomun ozelliklerini tasiyan vakalarin bulundugu bir spektrum olarak kabul edilebilir (8).
2-4) Classically, the Spitz nevus
presents as a dome-shaped, pink to reddish-brown papule or nodule, usually less than 6 mm in diameter.
Differential diagnoses included a pigmented epithelioid melanocytoma, an agminated Spitz nevus
, or a "low-grade" melanoma (Clark's level III, Breslow thickness 3.
is a well-known mimicker of melanoma, although Dr.
Differentiation of Spitz nevus
from spitzoid melanoma can be problematic, as exemplified by the number of cases sent for consultation.