spironolactone (redirected from Spironolacton)

spironolactone /spir·o·no·lac·tone/ (spi?rah-no-lak´ton) one of the spirolactones, an aldosterone inhibitor that blocks the aldosterone-dependent exchange of sodium and potassium in the distal tubule, thus increasing excretion of sodium and water and decreasing excretion of potassium; used in the treatment of edema, hypokalemia, primary aldosteronism, and hypertension.

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spi·ro·no·lac·tone (spr-n-lktn, sp-r-)

n.

An aldosterone antagonist and antiandrogen that promotes diuresis and is used to treat conditions characterized by hypertension and fluid retention as well as androgenic syndromes in women.

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spironolactone (spī´rnōlak´tōn),

n brand names: Aldactone, Spirozide;
drug class: potassium-sparing diuretic;
action: competes with aldosterone at receptor sites in distal tubule, resulting in excretion of sodium chloride and water and retention of potassium and phosphate;
uses: treatment for edema, hypertension, diuretic-induced hypokalemia, and cirrhosis of the liver with ascites.

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spironolactone

a competitive antagonist of aldosterone, used as a diuretic. It increases resorption of sodium in the distal renal tubules.