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sphingolipid
(redirected from Sphingolipids)

   Also found in: Encyclopedia, Wikipedia 0.01 sec.
sphingolipid /sphin·go·lip·id/ (sfing″go-lip´id) a lipid in which the backbone is sphingosine or a related base, the basic unit being a ceramide attached to a polar head group; it includes sphingomyelins, cerebrosides, and gangliosides.
sphin·go·lip·id (sfngg-lpd, -lpd)
n.
Any of a group of lipids, such as sphingomyelins or cerebrosides, that yield sphingosine or its derivatives upon hydrolysis.

sphingolipid
[sfing′gōlip′id]
Etymology: Gk, sphingein, to bind, lipos, fat
a compound that consists of a lipid and a sphingosine. It is found in high concentrations in the brain and other tissues of the nervous system, especially membranes.

sphingolipid [sfing″go-lip´id]
a phospholipid containing sphingosine (e.g., ceramides, sphingomyelins, gangliosides, and cerebrosides), occurring in high concentrations in the brain and other nerve tissue.

sphingolipid
one of the two dominant 'families' of lipids; a range of phospholipids containing sphingosine (e.g. ceramides, sphingomyelins, gangliosides and cerebrosides), occurring in high concentrations in the brain and other nerve tissue.


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15) Animal models have suggested that neurons distorted by accumulated sphingolipids directly activate inflammatory pathways and cause eventual apoptosis.
Reinforcing the Barrier Reinforcement of the barrier function requires ingredients such as ceramides, fatty acids, cholesterol, sphingolipids and phospholipids.
Dense segments--called lipid rafts--containing other lipids such as sphingolipids and cholesterol, interrupt these uniform layers; these enriched microdomains are densely populated with receptors and ion channels, both of which are important to the cell signalling system.
 
 
 
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