sphingolipid

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Related to Sphingolipids: sphingomyelin, Gangliosides

sphingolipid

 [sfing″go-lip´id]
a phospholipid containing sphingosine (e.g., ceramides, sphingomyelins, gangliosides, and cerebrosides), occurring in high concentrations in the brain and other nerve tissue.

sphin·go·lip·id

(sfing'gō-lip'id),
Any lipid containing a long-chain base like that of sphingosine (for example, ceramides, cerebrosides, gangliosides, sphingomyelins); a constituent of nerve tissue.

sphingolipid

/sphin·go·lip·id/ (sfing″go-lip´id) a lipid in which the backbone is sphingosine or a related base, the basic unit being a ceramide attached to a polar head group; it includes sphingomyelins, cerebrosides, and gangliosides.

sphingolipid

(sfĭng′gə-lĭp′ĭd, -lī′pĭd)
n.
Any of a group of lipids, such as the ceramides, that yield sphingosine or its derivatives upon hydrolysis. They are major components of cell membranes and play a role in signaling and regulatory functions.

sphingolipid

[sfing′gōlip′id]
Etymology: Gk, sphingein, to bind, lipos, fat
a compound that consists of a lipid and a sphingosine. It is found in high concentrations in the brain and other tissues of the nervous system, especially membranes.

sphin·go·lip·id

(sfing'gō-lip'id)
Any lipid containing a long-chain base like that of sphingosine (e.g., ceramides, cerebrosides, gangliosides, sphingomyelins); a constituent of nerve tissue.

sphingolipid

fatty constituent of nerve tissue

sphingolipid

one of the two dominant 'families' of lipids; a range of phospholipids containing sphingosine (e.g. ceramides, sphingomyelins, gangliosides and cerebrosides), occurring in high concentrations in the brain and other nerve tissue.
References in periodicals archive ?
Age- and sex-dependent change in stratum corneum sphingolipids.
The findings suggested that atherosclerosis led to perturbation of LPCs, bile acids and sphingolipids, which might be the pharmacological basis of XKS against AS.
In 2010, a study in yeast found that ORMDL3 protein inhibits sphingolipid de-novo synthesis.
Currently, there are several theories as to how the stored sphingolipids affect neuroimaging.
Dense segments--called lipid rafts--containing other lipids such as sphingolipids and cholesterol, interrupt these uniform layers; these enriched microdomains are densely populated with receptors and ion channels, both of which are important to the cell signalling system.
This technique employs commonly available chemicals, is not water-sensitive and allows for the conversion of fatty acid salts, as well as the acyl components in all lipid classes, such as triacylglycerols, phospholipids, sphingolipids, and waxes, to methyl esters using a simple direct single-vial digestion and esterification procedures.
It's rapidly expanding family of novel research assays and reagents for phospholipids, sphingolipids, and lysophospholipids provide the most advanced offering of its kind.
These compounds, including antibodies and their derivatives that specifically bind to sphingolipids and sphingolipid metabolites, are expected to find use in the diagnosis and treatment of various diseases and disorders, including cardiovascular/cerebrovascular diseases and cancer.
Structure of fatty acids and lipids: Introduction; Fatty-acid nomenclature; Fatty acids--main structural features; Saturated acids; Monoene acids; Methylene-interrupted polyene acids; Other unsaturated acids; Branched chain and cyclic acids; Oxygenated acids; Halogenated fatty acids; Introduction to lipid structure; Acylglycerols; Wax esters; Glycosyldiacylglycerols; Phospholipids; Ether lipids; Sphingolipids.
PL, together with cholesterol and sphingolipids, are omnipresent components of cell membranes and are therefore both structurally and functionally important (Olsen, 1998).
9) Such rafts permit the exclusion of host membrane proteins from the budding virus and the enrichment of the bud with cholesterol and sphingolipids.
It has been shown to inhibit sphingolipid biosynthesis as one mode of action and bears some structural similarity to sphingosine, a precursor to sphingolipids[6].