Speckled Pattern

speckled pattern,

an immunofluorescence pattern produced when serum from a patient with a particular connective tissue disease is placed in contact with human epithelial cells and stained with fluorochrome-labeled animal antisera. Fine, coarse, or large speckles are observed in disorders such as lupus erythematosus and rheumatoid arthritis.

---

Speckled Pattern

Imaging Image texture The background ‘canvas’ on which different echoes in an ultrasonogram are painted
Rheumatology An immunofluorescence pattern that may be seen when the human epithelial cell line, HEp-2, is stained with serum from patients with connective tissue diseases, especially SLE, but also mixed connective tissue disease (MCTD), sicca syndrome, Sjögren syndrome, polymyositis, rheumatoid arthritis, and drug-induced immune reactions