sparfloxacin


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sparfloxacin

 [spahr-flok´sah-sin]
a synthetic, broad-spectrum antimicrobial agent.

sparfloxacin

/spar·flox·a·cin/ (spahr-flok´sah-sin) a synthetic, broad-spectrum antimicrobial agent.

sparfloxacin

an antiinfective.
indications It is used to treat community-acquired pneumonia and chronic bronchitis caused by Klebsiella pneumoniae, Haemophilus influenzae, H. parainfluenzae, and Moraxella catarrhalis.
contraindications Known hypersensitivity to quinolones and photosensitivity prohibit its use.
adverse effects Life-threatening effects are leukopenia and pseudomembranous colitis. Other adverse effects are eosinophilia, anemia, flatulence, diarrhea, QT interval prolongation, vasodilation, rash, pruritus, and photosensitivity. Common side effects are headache, dizziness, insomnia, nausea, vomiting, and abdominal pain.

sparfloxacin

Zagam® Infectious disease An advanced, broad-spectrum–gram-negative bacilli, staphylococci fluoroquinolone with improved activity against streptococci and anaerobes, TB, MAC Indications Community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis Adverse effects Photosensitivity, GI upset. See Fluoroquinolone.
References in periodicals archive ?
12 Antibiotics used for antibiogram determination of the collected strains among FQ were: norfloxacin, ciprofloxacin, ofloxacin, enoxacin, moxifloxacin, and sparfloxacin and nalidixic acid.
marcescens NAUKP5 Antibiotics Serratia Antibiotics Serratia marcescens marcescens NAUKP5 NAUKP5 Norfloxacin S Oxacillin S Gentamicin S Erythromycin R Chloramphenicol S Nalidixic acid S Ciproflaxin S Tobramycin S Clarithromycin R Vancomycin S Co-Trimoxazole R Impenem S Azithromycin S Moxifloxacin S Penicillin S Ofloxacin S Amikacin S Sparfloxacin S Ampicillin S Levofloxacin S Amoxyclav S Colistin S Ceftriaxone S Augmentin S Kanamycin S Gatifloxacin S Streptomycin S R- Resistance; S-Susceptible
Comparative in vitro activities of DU-6859a, levofloxacin, ofloxacin, sparfloxacin, and ciprofloxacin against 387 aerobic and anaerobic bite wound isolates.
Bactericidal effects of levofloxacin in comparison with those of ciprofloxacin and sparfloxacin.
Other fluoroquinolones such as gemifloxacin, sparfloxacin, grepafloxacin, trovafloxacin, and garenoxacin have been shown to be effective against M.
The recruited subjects were divided into eight groups of fluoroquinolones: - Ofloxacin, Ciprofloxacin, Norfloxacin, Levofloxacin, Lomefloxacin, Moxifloxacin, Gemifloxacin and Sparfloxacin.
Table 1 shows single drug percentage price variation for various fluoroquinolones, which was as follows: ofloxacin (200 mg) 869%; sparfloxacin (200 mg) 648%; gemifloxacin (320 mg) 477%; norfloxacin (400 mg) 291%; ciprofloxacin (500 mg) 290%; levofloxacin (250 mg) 264%; lomefloxacin (400 mg) 104%; and moxifloxacin (400 mg) 60%.
The antibiotics used for AST were Ciprofloxacin, Gentamicin, Amikacin, Ceftazidime, Ceftriaxone, Ceftriaxone +Tazobactum, Sparfloxacin, Amoxicillin + Clavulanic acid, Cefepime + Tazobactam, Enrofloxacin, Oxacillin, Cefoxitin and Linezolid.
Significant increases in levofloxacin and sparfloxacin resistance were the most prominent (p<0.
The investigated antibiotics were Ciprofloxacin, Levofloxacin, Ofloxacin, Sparfloxacin, Ceftazidime, Ceftriaxone, and Cefotaxime.
Among fluoroquinolones, ciprofloxacin showed more resistance as compared to sparfloxacin.