Sotos syndrome (redirected from Sotos' syndrome)

Sotos syndrome [so´tōs]

cerebral gigantism.

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Sotos syndrome

Cerebral gigantism An AD condition with rapid early somatic growth of neonatal onset, that is not accompanied by endocrinopathy, accelerated bone maturation, or precocious puberty Clinical Macrosomia, where growth is accelerated for the first 4-5 yrs of life, followed by a normal growth pattern, enlarged acral parts–hands and feet, thickened subcutaneous tissues, macrocephaly, mild mental retardation and perceptual defects; EEG abnormalities, dilated ventricles, dolichocephaly, antimongolic slanting of palpebral fissures, macrognathy, hypertelorism, convulsions, poor coordination, ↑ risk for CA–eg, Wilms' tumor, liver, parotid, ovarian CAs