sorbitol

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sorbitol

 [sor´bĭ-tol]
a six-carbon sugar alcohol from a variety of fruits, found in lens deposits in diabetes mellitus. A pharmaceutical preparation is used as a sweetening agent and osmotic laxative, and in drugs as a tablet excipient, moistening agent, and stabilizer.

sor·bi·tol

(sōr'bi-tol),
A reduction product of glucose and sorbose found in the berries of the rowan/mountain ash, Sorbus aucuparia (family Rosaceae), and in many fruits and seaweeds. It has many industrial and pharmaceutical uses; medicinally, it is used as a laxative and as a sweetening agent, and is almost completely metabolized (to CO2 and H2O); accumulates in Type 1 diabetes mellitus; elevated levels can cause osmotic damage.
Synonym(s): sorbite

sorbitol

/sor·bi·tol/ (sor´bĭ-tol) a six-carbon sugar alcohol from a variety of fruits, found in lens deposits in diabetes mellitus. A pharmaceutical preparation is used as a sweetening agent and osmotic laxative, and in drugs as a tablet excipient, humectant, and stabilizer.

sorbitol

(sôr′bĭ-tôl′, -tōl′, -tŏl′)
n.
A white, sweetish, crystalline alcohol, C6H8(OH)6, found in various berries and fruits or prepared synthetically and used as a flavoring agent, a sugar substitute for people with diabetes, and a moisturizer in cosmetics and other products.

sorbitol

A polyhydroxyl alcohol or polyol synthesized from glucose by aldose reductase in neural tissue, produced in excess in DM; sorbitol may be further metabolized to fructose, which together cause ↑ osmotic pressure, intracellular edema, Schwann cell swelling, anoxia and nerve demyelination; it has been implicated in diabetic neuropathy; it has been used as an artificial sweetener. Cf Advanced glycosylation endproducts.

sor·bi·tol

(sōr'bi-tol)
Reduction product in many fruits and seaweeds that has many industrial and pharmaceutical uses; used as a laxative and as a sweetening agent.

sorbitol

A sweetening agent derived from glucose.

sor·bi·tol

(sōr'bi-tol)
Reduction product of glucose and sorbose found in the berries of rowan/mountain ash, Sorbus aucuparia, and in many other fruits and seaweeds. Has many industrial and pharmaceutical uses.

sorbitol

a sugar alcohol found in various berries and fruits; in mammals, sorbitol is an intermediate in the conversion of glucose to fructose. It is found in lens deposits in diabetes mellitus. A 50% solution is used as an osmotic diuretic. Sorbitol is used as a sweetener in some dietetic foods; it has the same caloric value as other sugars.

sorbitol dehydrogenase
called also SDH; see l-iditol dehydrogenase (ID).
References in periodicals archive ?
Sorbitol levels determined by sorbitol dehydrogenase and expressed as micromoles per gram of fresh gemmule tissue ([micro]mol/gfw) declined rapidly in germinating gemmules - from a maximum of about 36 [micro]mol/gfw to a steady-state level of about 4 [micro]mol/gfw by 36 h [ILLUSTRATION FOR FIGURE 2 OMITTED].
The activity of aspartate aminotransferase (AST), alanine aminotransferase (ALT), sorbitol dehydrogenase (SDH), glutamate dehydrogenase (GD), amylase (AMY) and lipase (LIP) was determined in homogenates of hepatopancreas, heart, abdominal muscle, proximal intestine, antennal gland, hemocyte lysate supernatant (HLS) and hemolymph plasma and serum.
4]-induced hepatic injury based on the serum activities of sorbitol dehydrogenase and aspartate aminotransferase.