sorbitol /sor·bi·tol/ (sor´bĭ-tol) a six-carbon sugar alcohol from a variety of fruits, found in lens deposits in diabetes mellitus. A pharmaceutical preparation is used as a sweetening agent and osmotic laxative, and in drugs as a tablet excipient, humectant, and stabilizer.
sorbitol
sor·bi·tol (sôr b -tôl , -t l)n. A white, sweetish, crystalline alcohol occurring naturally or prepared synthetically, used as a sugar substitute for people with diabetes. |
sorbitol
a sugar alcohol found in various berries and fruits; in mammals, sorbitol is an intermediate in the conversion of glucose to fructose. It is found in lens deposits in diabetes mellitus. A 50% solution is used as an osmotic diuretic. Sorbitol is used as a sweetener in some dietetic foods; it has the same caloric value as other sugars.
sorbitol dehydrogenase
called also SDH; see l-iditol dehydrogenase (ID).
sorbitol
A polyhydroxyl alcohol or polyol synthesized from glucose by aldose reductase in neural tissue, produced in excess in DM; sorbitol may be further metabolized to fructose, which together cause ↑ osmotic pressure, intracellular
edema, Schwann cell swelling, anoxia and nerve demyelination; it has been implicated in diabetic neuropathy; it has been used as an artificial sweetener. Cf Advanced glycosylation endproducts.
How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content.
| ?Page tools | ||
|---|---|---|
|